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Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib
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Establishment and Characterization of Three Afatinib-resistant Lung Adenocarcinoma PC-9 Cell Lines Developed with Increasing Doses of Afatinib

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Second-line erlotinib in an EGFR mutation-negative patient with non-small-cell lung cancer

Vera Hirsh1

  • 1Medical Oncology Department, MUHC Royal Victoria Hospital, 687 Pine Avenue West, Suite A3.04, Montreal, Quebec H3A 1A1, vera.hirsh@muhc.mcgill.ca.

Current Oncology (Toronto, Ont.)
|February 14, 2012
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Non-small-cell lung canceregfr mutationerlotinibgefitinib

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Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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