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Continuous apex to left ventricle blood flow pattern in hypertrophic cardiomyopathy with apical aneurysm and
Bill P C Hsieh1, James Tauras, Cynthia Taub
1Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York 10461, USA. billhsieh2003@yahoo.com
Insights
This study details a unique Doppler pattern in hypertrophic cardiomyopathy (HCM) showing continuous apex-to-left ventricle (LV) flow. This finding in apical ischemia may explain aneurysm formation in HCM patients.
Area of Science:
- Cardiology
- Medical Imaging
- Physiology
Background:
- Hypertrophic cardiomyopathy (HCM) is a genetic heart muscle disease.
- Left ventricular hypertrophy (LVH) is a common finding in HCM.
- Apical aneurysms are a recognized complication of HCM.
Observation:
- A 42-year-old female presented with chest pain, murmurs, and ECG findings of LVH.
- Echocardiography revealed HCM with apical aneurysm and LV cavity obstruction.
- Doppler interrogation showed continuous systolic and diastolic flow from apex to LV with a notched pattern.
Findings:
- Adenosine nuclear scintigraphy demonstrated apical myocardial ischemia.
- Coronary angiography showed no epicardial coronary obstruction.
- A novel Doppler pattern of continuous apex-to-LV flow was observed in HCM with apical ischemia.
Implications:
- This Doppler pattern may be indicative of apical ischemia in HCM.
- The observed flow pattern could contribute to apical aneurysm formation.
- Understanding this phenomenon enhances diagnostic capabilities for HCM complications.
Abstract:
A 42-year-old female presented with chest pain, noted to have systolic and diastolic murmurs on physical examination and left ventricular hypertrophy on the electrocardiogram. Echocardiography with contrast enhancement revealed hypertrophic cardiomyopathy (HCM) with apical aneurysm and mid left ventricular cavity obstruction. Doppler interrogation showed continuous systolic and diastolic flow from the apex to left ventricle (LV) with a transient deceleration giving rise to a notched pattern. Myocardial ischemia of the apex was demonstrated on adenosine nuclear scintigraphy without epicardial coronary obstruction on angiography. This case demonstrates a novel Doppler pattern with continuous apex to LV flow in HCM in the setting of apical ischemia that may account for the formation of the aneurysm.
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