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Related Concept Videos

Gastrointestinal Motility Disorders01:20

Gastrointestinal Motility Disorders

Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents01:18

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents

Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
Drugs Affecting GI Tract Motility: Serotonin Receptor Agonists01:23

Drugs Affecting GI Tract Motility: Serotonin Receptor Agonists

Serotonin, a crucial neurotransmitter synthesized by enterochromaffin cells, plays a cardinal role in regulating gastrointestinal (GI) motility. With over 90% of the body's total serotonin in the GI tract, its influence on digestive processes is profound. Serotonin is swiftly released upon various stimuli, such as food boluses or certain drugs, triggering intrinsic sensory neurons in the myenteric plexus and extrinsic vagal and spinal sensory neurons. This leads to the activation of the...
Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents01:20

Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents

Diarrhea is characterized by the occurrence of frequent, watery bowel movements. Various factors can trigger diarrhea, including viral or bacterial infections, foodborne illnesses, side effects from certain medications, and underlying digestive disorders. If not adequately managed, diarrhea can lead to complications such as dehydration, electrolyte imbalances, and nutrient deficiencies. Severe diarrhea can lead to significant weight loss, malnutrition, and weakened immune function.
Adsorbents...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Gastric Motility01:16

Gastric Motility

Gastric motility is the coordinated contraction and relaxation of stomach muscles that convert ingested food into chyme, a semi-liquid substance ready for further digestion in the intestines. The process begins with the vagus nerve inducing the relaxation of the smooth muscles in the fundus and body of the stomach, allowing these regions to expand and accommodate up to approximately 1.5 liters of food and liquid.
Peristaltic Waves and Chyme Formation
Upon food entry, the stomach initiates...

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Related Experiment Video

Updated: May 25, 2026

Using An In Vitro Tissue Perfusion System to Detect the Functional Activities of Isolated Intestinal Tubes in Real Time
06:01

Using An In Vitro Tissue Perfusion System to Detect the Functional Activities of Isolated Intestinal Tubes in Real Time

Published on: July 26, 2024

[Functional and motility gastrointestinal disorders].

Fermín Mearin1, Enrique Rey, Agustín Balboa

  • 1Instituto de Trastornos Funcionales y Motores Digestivos, Servicio de Aparato Digestivo, Centro Médico Teknon, Barcelona, España. mearin@dr.teknon.es

Gastroenterologia Y Hepatologia
|February 15, 2012
PubMed
Summary
This summary is machine-generated.

This review highlights key findings from the American Gastroenterology Association

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Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation
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Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation

Published on: September 11, 2012

Gastrointestinal Motility Monitor (GIMM)
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Gastrointestinal Motility Monitor (GIMM)

Published on: December 1, 2010

Related Experiment Videos

Last Updated: May 25, 2026

Using An In Vitro Tissue Perfusion System to Detect the Functional Activities of Isolated Intestinal Tubes in Real Time
06:01

Using An In Vitro Tissue Perfusion System to Detect the Functional Activities of Isolated Intestinal Tubes in Real Time

Published on: July 26, 2024

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation
09:44

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation

Published on: September 11, 2012

Gastrointestinal Motility Monitor (GIMM)
08:15

Gastrointestinal Motility Monitor (GIMM)

Published on: December 1, 2010

Area of Science:

  • Gastroenterology and clinical practice.
  • Physiopathology of functional gastrointestinal disorders.
  • Pharmacological and non-pharmacological treatments.

Context:

  • Digestive Diseases Week (DDW) 2011 showcased advancements in gastroenterology.
  • Technological innovations like impedancemetry and high-resolution manometry are now standard.
  • Growing evidence supports a biopsychosocial model for functional gastrointestinal disorders (FGID).

Purpose:

  • To summarize significant research presented at DDW 2011.
  • To evaluate the clinical utility of new diagnostic criteria and treatments for FGID.
  • To highlight emerging data on FGID pathogenesis and management.

Summary:

  • Technological advances are integrated into clinical practice.
  • The Rome III criteria show limitations in diagnosing functional dyspepsia subtypes.
  • New insights into genetic, inflammatory, and psychological factors in FGID, including functional dyspepsia and irritable bowel syndrome (IBS).
  • Efficacy of acotiamide, linaclotide, prucalopride, and biofeedback for constipation and FGID was discussed.
  • Special attention was given to rumination syndrome, esophageal pain, and cannabinoid hyperemesis syndrome.

Impact:

  • Consolidation of advanced diagnostic tools in gastroenterology.
  • Challenges in applying current diagnostic criteria for FGID.
  • Advancements in understanding and treating functional gastrointestinal disorders.
  • Evidence supporting biofeedback for dyssynergic constipation.
  • Identification of key areas for future research and clinical focus.