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Yabi: An online research environment for grid, high performance and cloud computing.

Adam A Hunter1, Andrew B Macgregor, Tamas O Szabo

  • 1Centre for Comparative Genomics, Murdoch, Western Australia, 6150. mbellgard@ccg.murdoch.edu.au.

Source Code for Biology and Medicine
|February 16, 2012
PubMed
Summary
This summary is machine-generated.

Yabi is an open-source workflow system simplifying complex life science analyses on high-performance computing (HPC) resources. It offers a drag-and-drop interface and command-line access for managing data and tools across distributed environments.

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Area of Science:

  • Life Sciences
  • Bioinformatics
  • Computational Biology

Background:

  • Significant demand exists for robust pipelines in life sciences to chain complex analysis tasks.
  • Existing workflow environments often present configuration challenges in heterogeneous computing and storage infrastructures.
  • Users face difficulties accessing HPC resources and managing data across distributed systems.

Purpose of the Study:

  • To introduce Yabi, an open-source software system designed to address complexities in life science workflow execution.
  • To enable seamless and transparent access to heterogeneous high-performance computing (HPC) environments.
  • To provide a flexible and secure environment for creating, reusing, and managing analysis workflows and large datasets.

Main Methods:

  • Described the architecture of the Yabi software system.
  • Implemented pluggable execution and data backends for adaptability.
  • Developed both a web-based drag-and-drop interface and a command-line interface for user interaction.
  • Enabled simplified tool configuration for system administrators via a web interface.

Main Results:

  • Yabi provides an adaptable analysis workflow environment with pluggable backends.
  • It enables secure and flexible management of large datasets across geographically distributed compute resources.
  • The system simplifies tool configuration, reducing overhead for users and administrators.
  • Demonstrated Yabi's utility through bioinformatics use cases in large-scale biomedical data analysis.

Conclusions:

  • Yabi abstracts technical HPC complexities, offering an intuitive, scalable, web-based workflow environment.
  • Users can access tools via drag-and-drop or a command-line interface.
  • Yabi is deployed at multiple institutions and available for use.