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Updated: May 24, 2026

Quail Chorioallantoic Membrane - A Tool for Photodynamic Diagnosis and Therapy
Published on: April 28, 2022
Photodynamic therapy in the management of circumscribed choroidal hemangioma
Javier Elizalde1, LuzMaría Vasquez, Fernando Iyo
1Institut Universitari Barraquer, Universitat Autònoma de Barcelona, Barcelona, Spain. javierelizalde@barraquer.com
Objective:
To evaluate the efficacy of photodynamic therapy (PDT) for symptomatic circumscribed choroidal hemangioma (CCH).
Design:
A retrospective case series analysis through chart review of patients with CCH treated by means of PDT.
Participants:
Thirteen patients with circumscribed choroidal hemangioma.
Methods:
Through retrospective charts review, the patients' demographics, clinical features, management, and follow-up data were obtained and analyzed. Outcome measures were change in visual acuity, required sessions, and adjunctive treatments.
Results:
Median follow-up was 26 months. Seven patients (54%) underwent only 1 session, 5 patients (38%) 2 sessions, and 1 received 5 sessions and was finally treated with external beam radiotherapy (EBRT). Visual acuity improved by at least 1 line (1-5) in 11 patients and remained stable in 2. Exudative subretinal fluid was completely resolved in 92% of the cases at the last visit. No major local side effects were found.
Conclusions:
PDT of CCH can effectively induce tumor regression and resolution of exudative subretinal fluid, improving, or stabilizing vision.
