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Published on: July 11, 2025
Non-invasive cryolipolysis for body contouring in Chinese--a first commercial experience
Samantha Y Shek1, Nicola P Y Chan, Henry H Chan
1Division of Dermatology, Department of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Background:
The objective of the study is to determine the clinical efficacy and patient satisfaction of a novel cryolipolysis device (Zeltiq®) for body contouring in Chinese after a single treatment and after 2 treatments at a commercial setting.
Materials And Methods:
Two groups of patients were recruited for this procedure at their own cost. Group A, 21 subjects, received a single treatment and group B, 12 subjects, received 2 treatments, average 3 months apart using the Zeltiq Breeze System®. The thickness of fat at the treatment site was measured by a caliper and the data were collected at baseline and 2 months post-treatment. Standardized clinical photos were also taken at baseline and follow-up visits. Subjective assessment was carried out in the form of a questionnaire. Any adverse effects were documented. Statistical analyses were performed on the data to compare the efficacy after a single treatment and after 2 treatments.
Results:
The first group of subjects, received a single treatment, showed that there was a significant improvement (P < 0.0001). The second group of subjects showed that the improvement was significant after 1 and 2 treatments when compared to the baseline. The extent of improvement after the second treatment however, was not as dramatic as the first treatment.
Conclusion:
Non-invasive cryolipolysis is effective for body contouring in Chinese. It is shown to have a further improvement with subsequent treatment sessions but of a lesser extent. The second treatment was statistically significant for abdomen, though not for love handles.

