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Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
A Turkish perspective on coronary artery bypass surgery and percutaneous coronary artery intervention in chronic
Güliz Kozdag1, Gökhan Ertas, Ender Emre
1Department of Cardiology, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey.
Insights
Coronary revascularization, including bypass surgery and stenting, may improve outcomes for patients with systolic heart failure and coronary artery disease. These interventions show better prognosis compared to no revascularization in SHF patients.
Area of Science:
- Cardiology
- Cardiac Surgery
- Interventional Cardiology
Background:
- Systolic heart failure (SHF) poses significant mortality risks.
- The comparative impact of coronary revascularization on clinical outcomes in SHF patients remains unclear.
- Coronary artery disease (CAD) is a common comorbidity in SHF.
Purpose of the Study:
- To evaluate the impact of coronary artery bypass graft (CABG) surgery and stent implantation on clinical outcomes in patients with systolic heart failure.
- To compare outcomes between different revascularization strategies and no revascularization in SHF patients with CAD.
Main Methods:
- Retrospective analysis of 637 patients hospitalized for decompensated SHF.
- Categorization of patients based on the presence or absence of coronary artery disease (CAD).
- Comparison of clinical outcomes, including cardiovascular mortality, among patients who underwent stenting alone, CABG surgery plus stenting, and no revascularization.
Main Results:
- 35% of SHF patients died from cardiovascular causes during follow-up.
- Patients with SHF and CAD who underwent stenting alone or CABG surgery plus stenting demonstrated a significantly better prognosis compared to those with CAD but no revascularization (P < .001 and P = .013, respectively).
Conclusions:
- Coronary revascularization procedures, specifically stenting and combined CABG with stenting, may offer a survival benefit in patients with systolic heart failure and coronary artery disease.
- These findings suggest that revascularization should be considered in the management of SHF patients with concomitant CAD.
Abstract:
The impact of coronary revascularization methods (coronary artery bypass graft [CABG] surgery and stent implantation) on clinical outcome has not been determined yet in patients with systolic heart failure (SHF). We examined outcomes in patients discharged from our hospital after hospitalization for decompensated SHF. Of 637 patients with SHF (mean age, 64 ± 13 years; mean ejection fraction, 26.5% ± 9%), 402 patients (63%) had coronary artery disease (CAD) and 235 patients (37%) had no CAD; 223 patients (35%) died because of cardiovascular reasons during follow-up. Patients who had stenting alone and patients who had CABG surgery and stenting had better prognosis than patients with CAD but no revascularization procedure (P < .001 and P = .013, respectively). In the patients with SHF having CAD who had stenting and CABG surgery + stenting may have better prognosis compared with patients with CAD who had no revascularization procedure in their past.
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