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Related Concept Videos

Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.

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Surgical Bone Implantation Technique for Rat Tibia Models of Diabetes and Osteoporosis
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Osteogenesis at implants without primary bone contact - an experimental study in dogs.

Stefano Sivolella1, Eriberto Bressan, Luiz A Salata

  • 1Faculty of Dentistry, University of Medical Science, La Habana, Cuba.

Clinical Oral Implants Research
|February 17, 2012
PubMed
Summary

Dental implants showed limited osseointegration when placed in larger bone defects, indicating defect size impacts healing. Further research is needed to improve implant success in challenging sites.

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An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
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Published on: February 10, 2014

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An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
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An Improved Mechanical Testing Method to Assess Bone-implant Anchorage

Published on: February 10, 2014

Area of Science:

  • Oral surgery
  • Biomaterials science
  • Dental implantology

Background:

  • Osseointegration is crucial for dental implant success.
  • Understanding bone healing around implants in compromised sites is essential.
  • Previous studies have not fully explored implant healing in intentionally created bone defects.

Purpose of the Study:

  • To evaluate osseointegration of dental implants in surgically created bone defects of varying sizes.
  • To assess the influence of defect dimensions on bone-implant contact and soft tissue integration.
  • To compare healing outcomes between implants in defects and control implants in native bone.

Main Methods:

  • Dental implants with a moderately rough surface were placed in mandibular alveolar bone defects (0.7 mm and 1.2 mm) in dogs.
  • Control implants were placed in native bone without defects.
  • Implants were stabilized to prevent contact with the defect walls, and healing was assessed after 3 months via histomorphometry.

Main Results:

  • Bone-implant contact (BIC) was significantly lower in defect sites (5.3% and 0.3%) compared to controls (46.1%).
  • Dense connective tissue (DCT) covered most of the implant surface in defect sites (92.8% and 95.6%).
  • Residual defect widths were minimal (0.4-0.5 mm), suggesting limited bone fill.

Conclusions:

  • Osseointegration occurred at a very low level in both small and large defects.
  • The size of the created bone defect influenced the degree of osseointegration.
  • Significant differences in BIC highlight the challenge of achieving robust osseointegration in non-contained defects.