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Updated: May 24, 2026
Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities
Published on: January 29, 2014
A positive wave at 8 ms (P8) and modified auditory brainstem responses measurement in auditory neuropathy spectrum
Claus-Michael Schmidt1, Jan Robin Huebner, Dirk Deuster
1Muenster University Hospital, Department of Phoniatrics and Pedaudiology, Kardinal-von-Galen-Ring 10, 48129 Muenster, Germany. michael.schmidt@uni-muenster.de
Objective:
Auditory neuropathy spectrum disorder (ANSD) is characterized by absent or atypical auditory brainstem responses (ABR), recordable otoacoustic emissions and/or cochlear microphonics. Modification of ABR stimuli is discussed to improve wave V synchronization in ANSD patients.
Design:
Ten ANSD children (seven unilateral) underwent ABR measurement with an alternating stimulus (40.5s(-1)), constant rarefaction and condensation stimuli, a reduced click-rate (11.1s(-1)) and a chirp-stimulus.
Results:
The results showed no remarkably better synchronization with modified stimuli. Whereas higher levels showed no synchronization, reproducible positive waves at 8 ms (P8) at intensities of 65-85 dB were found in six patients with all stimuli.
Conclusions:
We suggest an ipsilateral auditory origin of the positive potentials at 8 ms. They could be characteristic of synchronization abnormalities in some cases of ANSD.
