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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Veins of Head and Neck01:19

Veins of Head and Neck

The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...

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Related Experiment Video

Updated: May 24, 2026

A Model for Perineural Invasion in Head and Neck Squamous Cell Carcinoma
08:59

A Model for Perineural Invasion in Head and Neck Squamous Cell Carcinoma

Published on: January 5, 2017

Head and neck polypoid melanoma.

Mario Dini1, Fabio Quercioli, Valentina Caldarella

  • 1Department of Plastic and Reconstructive Surgery, University of Florence, Largo Palagi, Florence, Italy.

The Journal of Craniofacial Surgery
|February 17, 2012
PubMed
Summary
This summary is machine-generated.

Polypoid melanoma, a rare skin cancer variant, typically affects younger adults on the back and has a poorer prognosis. This case highlights an unusual presentation in an older man on the face.

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Last Updated: May 24, 2026

A Model for Perineural Invasion in Head and Neck Squamous Cell Carcinoma
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Area of Science:

  • Dermatology
  • Oncology
  • Surgical Pathology

Background:

  • Polypoid melanoma is a rare clinical variant of nodular melanoma.
  • It is characterized by exophytic growth, ulceration, and a pedicle attachment.
  • This subtype typically affects younger individuals (20-39 years) primarily on the back.

Observation:

  • A deeply pigmented polypoid melanoma was observed on the face of a 77-year-old male patient.
  • This presentation is atypical given the usual demographic and anatomical predilection for polypoid melanoma.

Findings:

  • Polypoid melanoma exhibits a lower 5-year survival rate (32-42%) compared to nodular (57%) and superficial (77%) melanoma subtypes.
  • The case presented an unusual facial location and older age of onset.

Implications:

  • This case underscores the importance of considering rare melanoma variants even in atypical patient demographics and locations.
  • Further literature review is necessary to clarify optimal surgical management and prognostic factors for facial polypoid melanoma.
  • Understanding these variations is crucial for accurate diagnosis and treatment planning in melanoma patients.