Related Experiment Video
Updated: May 24, 2026

04:19
Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
Published on: November 8, 2024
[Inicidental finding: patient with cervical spine trauma]
M Schmidt1, C Abächerli, T Niemann
1Klinik für Radiologie und Nuklearmedizin, Universitätsspital Basel.
Praxis
|February 17, 2012
Summary
Ossification of the posterior longitudinal ligament (OPLL) can be asymptomatic but may lead to myelopathy after trauma. Early clinical consideration aids diagnosis and treatment for this spinal condition.
Area of Science:
- Orthopedics
- Neurosurgery
- Spinal Surgery
Background:
- Ossification of the posterior longitudinal ligament (OPLL) is a degenerative condition affecting the spine.
- OPLL often remains asymptomatic, posing diagnostic challenges.
- Trauma can precipitate symptomatic myelopathy in individuals with pre-existing OPLL.
Observation:
- Trauma can precipitate symptomatic myelopathy in individuals with pre-existing OPLL.
- The clinical presentation can be sudden and severe following an injury.
Findings:
- OPLL, even when asymptomatic, is a significant risk factor for developing myelopathy post-trauma.
- Prompt recognition of OPLL is essential for timely intervention.
Implications:
- Clinicians must consider OPLL in the differential diagnosis of myelopathy, especially after spinal trauma.
- Early diagnosis and management of OPLL can prevent irreversible neurological damage and improve patient outcomes.
Related Concept Videos
Herniated Intervertebral Disc l: Introduction
Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
Spinal Cord Injury ll: Pathophysiology
Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...
Secondary Spinal Cord Injury llI: Pathophysiology
Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...
