Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic01:26

Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic

Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Bacterial Phylum Actinobacteria01:30

Bacterial Phylum Actinobacteria

Coryneform bacteria are gram-positive, aerobic, nonmotile rods that exhibit irregular, club-shaped, or V-shaped arrangements. Their V-shape results from snapping division, where the inner cell wall layer forms the cross-wall, while the outer layer remains intact until it ruptures on one side, causing the daughter cells to bend away.The primary genera are Corynebacterium and Arthrobacter. Corynebacterium includes diverse species, ranging from saprophytes to pathogens like Corynebacterium...
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Phylogenetic Analysis and Structural Evaluation of <i>Staphylococcus aureus</i> Serine-Aspartate Repeat-Containing Protein D with a Focus on Periprosthetic Joint Infection.

bioRxiv : the preprint server for biology·2026
Same author

Resistance to novel β-lactam/β-lactamase inhibitors among carbapenem-resistant <i>Pseudomonas aeruginosa</i> and clinical implications in the prospective observational <i>Pseudomonas</i> study.

Antimicrobial agents and chemotherapy·2026
Same author

Treatment of Severe Ocular Mpox with Cidofovir and Tecovirimat.

Emerging infectious diseases·2026
Same author

Escherichia coli ST131 Drives Carbapenem Use for E. Coli Bloodstream Infections.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same author

Addictive disorders and correlates in the context of chemsex practices: A French online survey.

Addictive behaviors reports·2026
Same author

Clinical and Organizational Determinants of a Frequently Delayed Diagnosis of Ocular Syphilis in a French Referral Center.

American journal of ophthalmology·2025
Same journal

The Brief Case: Wound infection following a penetrating and cutting instrument injury: a case report.

Journal of clinical microbiology·2026
Same journal

Ebola laboratory preparedness at frontline hospitals: can we or can't we?

Journal of clinical microbiology·2026
Same journal

Reporting macrolide-resistant <i>Mycoplasma pneumoniae</i>: a diagnostic obligation?

Journal of clinical microbiology·2026
Same journal

Diagnostic value of HHV-6A/B genotyping in immunocompromised adults.

Journal of clinical microbiology·2026
Same journal

Multicenter performance evaluation of the Simplexa <i>C. auris</i> Direct assay for the detection of <i>Candida auris</i> colonization in bilateral axilla/groin swabs.

Journal of clinical microbiology·2026
Same journal

Comparison of blood culture contamination rates with standard practice versus two blood diversion devices at a single institution.

Journal of clinical microbiology·2026
See all related articles

Related Experiment Video

Updated: May 24, 2026

A Periprosthetic Joint Candida albicans Infection Model in Mouse
04:37

A Periprosthetic Joint Candida albicans Infection Model in Mouse

Published on: February 2, 2024

Corynebacterium prosthetic joint infection.

Charles Cazanave1, Kerryl E Greenwood-Quaintance, Arlen D Hanssen

  • 1Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.

Journal of Clinical Microbiology
|February 17, 2012
PubMed
Summary
This summary is machine-generated.

A new PCR assay rapidly identifies common Corynebacterium species, including those causing prosthetic joint infection (PJI). This tool aids in diagnosing PJI and differentiating antibiotic-resistant strains.

More Related Videos

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
10:35

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Published on: December 3, 2017

Related Experiment Videos

Last Updated: May 24, 2026

A Periprosthetic Joint Candida albicans Infection Model in Mouse
04:37

A Periprosthetic Joint Candida albicans Infection Model in Mouse

Published on: February 2, 2024

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
10:35

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Published on: December 3, 2017

Area of Science:

  • Microbiology
  • Molecular Diagnostics
  • Infectious Diseases

Background:

  • Accurate identification of Corynebacterium species is crucial for clinical management.
  • Corynebacterium species are implicated in prosthetic joint infections (PJI), yet data remain limited.
  • Commonly implicated species include C. amycolatum, C. aurimucosum, C. jeikeium, and C. striatum.

Observation:

  • A novel, rapid PCR assay was developed to detect common human Corynebacterium species.
  • The assay targets a polyphosphate kinase gene identified through whole-genome sequencing.
  • It differentiates antibiotic-resistant species like C. jeikeium and C. urealyticum.

Findings:

  • The assay successfully detected clinically relevant Corynebacterium species in various human isolates.
  • All Corynebacterium isolates specifically associated with PJI were accurately identified.
  • The study reports the first documented case of prosthetic joint infection caused by C. simulans.

Implications:

  • This PCR assay offers a rapid and accurate diagnostic tool for Corynebacterium identification in clinical settings.
  • It can improve the diagnosis and management of prosthetic joint infections.
  • The assay's ability to differentiate antibiotic-resistant strains is vital for treatment decisions.