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Related Experiment Video

Updated: May 24, 2026

An R-Based Landscape Validation of a Competing Risk Model
05:37

An R-Based Landscape Validation of a Competing Risk Model

Published on: September 16, 2022

Risk-management syndrome.

Masaaki Tanaka1, Yasuyoshi Watanabe

  • 1Department of Physiology, Osaka City University Graduate School of Medicine, Osaka, Japan. masa-t@msic.med.osaka-cu.ac.jp

International Journal of Psychiatry in Clinical Practice
|February 21, 2012
PubMed
Summary
This summary is machine-generated.

Modern life triggers ancient survival systems, leading to over-activated risk-management and potential illness. This study defines risk-management syndrome as a condition arising from chronic stress without organic damage.

Related Experiment Videos

Last Updated: May 24, 2026

An R-Based Landscape Validation of a Competing Risk Model
05:37

An R-Based Landscape Validation of a Competing Risk Model

Published on: September 16, 2022

Area of Science:

  • Evolutionary biology
  • Neuroscience
  • Public health

Background:

  • Organisms require starvation-resistance and risk-management for survival.
  • Humans evolved these systems for ancient threats, not modern stressors.
  • Urbanization frequently over-activates the human risk-management system.

Purpose of the Study:

  • To investigate the impact of modern stressors on ancient survival systems.
  • To define and classify illnesses arising from over-activated risk-management.
  • To identify key syndromes associated with urbanization.

Main Methods:

  • Conceptual analysis of evolutionary adaptation and stress response.
  • Definition of 'risk-management syndrome' based on pathophysiological mechanisms.
  • Classification of urbanization-associated syndromes.

Main Results:

  • Repeated modern stressors can lead to central sensitization and classical conditioning of the risk-management system.
  • Risk-management syndrome is characterized by over-activation without apparent organic damage.
  • Risk-management and metabolic syndromes are identified as major syndromes linked to urbanization.

Conclusions:

  • Urbanization poses unique challenges to human adaptation.
  • Over-activation of the risk-management system can result in distinct pathological syndromes.
  • Understanding these syndromes is crucial for public health in urban environments.