An effective night slimming topical treatment

Area of Science:

• Dermatology
• Cosmetic Science
• Bioengineering

Background:

• Sex-specific fat accumulation presents both physiological and cosmetic challenges.
• Topical treatments offer a non-invasive alternative for managing localized fat deposits.
• Botanical extracts are increasingly utilized for their potential in cosmetic applications, targeting processes like adipolysis and microcirculation.

Purpose of the Study:

• To evaluate the efficacy and tolerability of a novel topical product formulated with botanical extracts for reducing localized fat.
• To assess the product's effects on adipolysis and microcirculation, particularly during nighttime application.
• To compare the topical product against a placebo using objective bioengineering and clinical assessments.

Main Methods:

• A double-blind, placebo-controlled trial involving 100 subjects across two research centers in Italy.
• In vivo evaluation using high-frequency ultrasonography for skin bioengineering measurements.
• Clinical assessments and instrumental evaluations conducted over a 4-week period with four follow-up visits.

Main Results:

• The topical product demonstrated statistically significant slimming effects compared to the placebo.
• Ultrasonography measurements confirmed improvements in skin structure and fat reduction.
• The product exhibited good tolerability, with no adverse events reported.

Conclusions:

• The tested topical product, formulated with botanical extracts, is effective in reducing localized fat and improving skin appearance.
• Nighttime application leverages the body's natural physiological processes for enhanced results.
• The product represents a safe and satisfactory non-invasive option for individuals seeking to address cosmetic concerns related to sex-specific fat.