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The effect of mycophenolic acid on the cell cycle of Candida albicans
C M Quinn1, V C Bugeja, J A Gallagher
1Biology Department, Maynooth College, Ireland.
Mycopathologia
|September 1, 1990
Abstract:
Mycophenolic acid inhibited the growth of Candida albicans. Cultures exposed to a concentration of 8.4 micrograms ml-1 mycophenolic acid were found to exhibit cell cycle arrest with two or more buds. Nuclear staining revealed that these were nucleate implying a possible defect in cytokinesis. The results are discussed in relation to the possible mode of action of mycophenolic acid.