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Helicobacter pylori in middle ear of children with otitis media with effusion

Chul-Won Park1, Jae-Ho Chung, Hyun-Jung Min

  • 1Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Hanyang University, Seoul, Korea.

Chinese Medical Journal
|February 21, 2012
PubMed
Abstract

Insights

Helicobacter pylori (HP) infection may cause otitis media with effusion (OME) in children. This study found HP in 30% of OME patients, suggesting a link between HP and OME development.

Area of Science:

  • Pediatric Otolaryngology
  • Infectious Diseases
  • Microbiology

Background:

  • Otitis media with effusion (OME) is a prevalent pediatric condition with unclear origins.
  • The potential role of Helicobacter pylori (HP) in OME pathogenesis is under investigation.
  • Existing research has not definitively established a link between HP and OME.

Purpose of the Study:

  • To investigate the association between Helicobacter pylori (HP) and otitis media with effusion (OME).
  • To determine if HP is present in middle ear effusions of children with OME.

Main Methods:

  • A cohort of 60 OME patients undergoing ventilation tube insertion and 30 adenoidectomy-only patients were studied.
  • Middle ear effusion samples were analyzed using polymerase chain reaction (PCR) and the campylobacter-like organism (CLO) test.
  • Adenoid tissue samples were also analyzed for HP presence using the CLO test.

Main Results:

  • Helicobacter pylori (HP) was detected in 30% of OME patients.
  • HP was found in 15.6% of OME patients' adenoid tissue and 13.3% of control adenoid tissue.
  • No significant difference in HP prevalence was observed between OME and control groups in adenoid tissues.

Conclusions:

  • The findings suggest that Helicobacter pylori (HP) is a potential causative agent of otitis media with effusion (OME).
  • Further research is warranted to elucidate the precise mechanisms of HP involvement in OME.

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