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Coordinating tissue interactions: Notch signaling in cardiac development and disease

José Luis de la Pompa1, Jonathan A Epstein

  • 1Program of Cardiovascular Developmental Biology, Department of Cardiovascular Development and Repair, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Melchor Fernández Almagro 3, E-28029 Madrid, Spain. jlpompa@cnic.es

Developmental Cell
|February 21, 2012
PubMed
Summary

The Notch pathway regulates heart development, particularly in endocardial cells, influencing chamber and valve formation. It also plays roles in cardiomyocyte growth and blood vessel development, with implications for heart diseases.

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