Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Endocarditis III: Medical Management

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...

Cystic Fibrosis: Management

Cystic Fibrosis: Management

Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic sinusitis...

Brain Abscess l: Introduction

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...

Herniated Intervertebral Disc l: Introduction

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...

Pneumonia IV: Management

Pneumonia IV: Management

The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:

Varicose Veins II: Diagnostic Studies and Interprofessional Care

Varicose Veins II: Diagnostic Studies and Interprofessional Care

Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Imaging findings of acute sport-related osseous avulsions and osteochondral injuries.

Skeletal radiology·2026

Same author

Endocarditis caused by Candida (Candidozyma) auris.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases·2026

Same author

Guide to lower extremity radiologic measurements: part 1 hip.

Skeletal radiology·2026

Same author

Guide to lower extremity radiologic measurements: part 3 ankle and foot.

Skeletal radiology·2026

Same author

Guide to lower extremity radiologic measurements: part 2 knee.

Skeletal radiology·2026

Same author

Ten-year pathology-based cancer registry at a tertiary referral hospital in Kenya (2015-2024): distribution of cancers and completeness of pathology reporting.

BMC cancer·2026

Search research articles

Related Experiment Video

Updated: May 24, 2026

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

Vertebral coccidioidomycosis: presentation and multidisciplinary management.

Larissa A Szeyko¹, Mihra S Taljanovic, Robert B Dzioba

¹Infectious Disease Section, University of Arizona College of Medicine, Tucson, 85724-5039, USA.

The American Journal of Medicine

|February 21, 2012

Summary

Vertebral coccidioidomycosis, a severe complication of Coccidioides infection, often requires surgery and antifungal therapy. Discontinuation of treatment poses a high risk of relapse, even years later.

More Related Videos

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

Published on: October 25, 2024

Related Experiment Videos

Last Updated: May 24, 2026

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

Published on: October 25, 2024

Area of Science:

Infectious Diseases
Mycology
Orthopedic Surgery

Background:

Vertebral involvement is a severe complication of Coccidioides fungal infections.
Coccidioidomycosis can affect the spine, leading to significant morbidity.

Purpose of the Study:

To review cases of vertebral coccidioidomycosis.
To analyze treatment outcomes and identify risk factors for relapse.

Main Methods:

Retrospective review of patients diagnosed with vertebral coccidioidomycosis.
Data collected from 1996 to 2009 at an academic medical center.

Main Results:

39 cases identified; 79% male, 61% Black patients (50-fold increased odds).
Most patients (80%) were immunocompetent; 67% required surgery for pain or neurologic compromise.
All received triazoles; 20 also received amphotericin B. Relapse occurred in 6 patients after stopping antifungal therapy.

Conclusions:

Vertebral coccidioidomycosis necessitates a multidisciplinary approach with medical and often surgical management.
Favorable outcomes are achievable, but long-term antifungal therapy is crucial to prevent late relapses.