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Published on: July 31, 2014
[Cerebellar infarction: prognosis and complications of vascular territories]
L M Cano1, P Cardona, H Quesada
1Servicio de Neurología, Hospital Universitari de Bellvitge, IDIBELL, L'Hospitalet de Llobregat, Barcelona, España. lcano@bellvitgehospital.cat
Insights
Cerebellar infarction (CI) is uncommon, with posterior inferior cerebellar artery (PICA) strokes being most frequent and often caused by atherothrombosis. These PICA strokes are linked to severe complications like hydrocephalus and worse disability outcomes.
Area of Science:
- Neurology
- Vascular Neurology
- Neuroimaging
Context:
- Cerebellar infarction (CI) is an uncommon cerebrovascular event.
- CI can lead to significant neurological deficits and complications.
- Understanding CI characteristics and outcomes is crucial for patient management.
Purpose:
- To characterize patients with cerebellar infarction (CI).
- To identify the most commonly affected cerebellar arteries.
- To determine the etiological factors and outcomes associated with CI.
Summary:
- A study of 124 patients revealed that the posterior inferior cerebellar artery (PICA) was the most frequently affected territory (49.2%).
- Atherothrombosis was the primary cause of PICA infarction, while cardio-embolism was linked to multi-territory involvement.
- Complications such as hemorrhagic transformation and hydrocephalus were observed, with worse disability outcomes in patients with multi-territory involvement.
Impact:
- Highlights PICA infarction as the most common type of CI.
- Identifies atherothrombosis as a key etiology for PICA strokes.
- Emphasizes the association of PICA territory involvement with severe complications within the first week post-stroke.
Introduction:
Cerebellar infarction (CI) is uncommon, but may result in severe complications. The aim of our study was to determine the characteristics of patients with CI, as well as their outcomes as regards the territories affected.
Patients And Methods:
Data were collected from 124 patients admitted to our department during a five-year period, with a radiological diagnosis of CI, and with or without involvement of other brain territories.
Results:
The mean age in our series was 65.2 years, with most being male (68.5%). The posterior inferior cerebellar artery (PICA) was the most commonly affected territory at 49.2%, followed by superior cerebellar artery (SCA) at 17.7%, and anterior inferior cerebellar artery (AICA) at 10.5%. There was simultaneous supratentorial involvement in 13.7%, and two or three cerebellar arteries involved in 8.9%. The main aetiology in PICA was atherothrombosis (P=.02). On the other hand, cardio-embolism was the main origin in cases with more than one affected territory (P=.04). No particular aetiology could be found in SCA and AICA. There was haemorrhagic transformation in 29 patients (23.4%), particularly in the PICA and when other territories were involved. There was hydrocephalus in 15 patients (12.1%, 12 of them PICA; P=.02) in 2.9 ± 1.5 days from stroke onset. At discharge, the degree of disability was worse if more than one arterial territory was involved (Rankin ≥ 3, 64% versus 31-36%; P=.05). Four (3.2%) patients died.
Conclusions:
CI is very heterogeneous. Nevertheless, it is noteworthy that PICA infarction is the most frequent type and its aetiology is usually atherothrombotic. Moreover, it is the territory most frequently associated with severe complications, which take place during the first week of the stroke.
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