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Updated: May 24, 2026
Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
[Prognostic factors of colorectal cancer lung metastases]
Núria Prenafeta Claramunt1, Vicenç Artigas Raventós, Guillermo Gómez Sebastián
1Servicio de Cirugía Torácica, Hospital de la Santa Creu i Sant Pau (Unidad docente de la Universidad autónoma de Barcelona [UAB]), Mancomunidad, Hospital Universitario Mutua Terrassa-Hospital de la Santa Creu i Sant Pau-Hospital de Mar (HUMT-HSCSP-HM), Barcelona, España. tempelakius@gmail.com
Introduction:
Colorectal cancer is the third most common neoplasia and the second cause of death due to cancer in developed countries. Approximately 10% of patients with this diagnosis develop lung metastases, although only 2-4% of them have lung metastases as the only extension location.
Objective:
To study the prognostic factors of colorectal cancer lung metastases.
Patients And Methods:
A retrospective observational study was conducted on 30 patients with colorectal cancer lung metastases who were operated on in our hospital between January 2003 and December 2007.
Results:
Of the 30 patients who received surgery, 19 were males (63%) and 11 were female (37%), with a mean age of 63.37 years (range 35-82 years). The mean overall survival was 36.64 months (range 18.58-54.70 months). A total of 13 pre-, intra-, and postoperative parameters were used in the statistical analysis. In the univariate analysis, the number of metastases greater than 3 (P=.051), whether they were bilateral (P=.001), or bilobar (P<.001), were statistically significant factors of a poor prognosis. In the multivariate analysis, only being bilobar was shown to be a statistically significant factor of a poor prognosis (P=.005).
Conclusions:
In our patient series affected by colorectal carcinoma lung metastases, the number of metastases greater than three, whether they are bilobar and bilateral, are factors of a poor prognosis. These factors should be taken into account in the follow-up of these patients, although prospective studies with a larger number of patients are required to confirm these findings.