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Updated: Oct 23, 2026

Murine Model of Central Venous Stenosis using Aortocaval Fistula with an Outflow Stenosis
Published on: July 11, 2019
[Rapid development of mitral and aortic stenoses with chronic hemodialysis. A report of 2 cases]
M Haziza1, M Terdjman, O Dubourg
1Service de Cardiologie, Hôpital Ambroise Paré, Boulogne.
Insights
Chronic renal failure patients often develop mitral and aortic valve calcifications. Echocardiography with Doppler is crucial for diagnosing aortic stenosis in hemodialysis patients, as clinical signs can be misleading.
Area of Science:
- Nephrology
- Cardiology
- Valvular Heart Disease
Background:
- Chronic renal failure (CRF) is linked to increased mitral annular calcification, potentially causing mitral stenosis or regurgitation.
- Aortic valve calcification is less common but can lead to aortic valve stenosis.
Observation:
- Two patients with hemodialysis-associated calcific aortic stenosis were observed.
- Clinical diagnosis of valvular aortic stenosis in hemodialysis patients can be challenging due to confounding factors like aortic sclerosis and left ventricular hypertrophy.
Findings:
- Calcific aortic stenosis can occur in patients with chronic renal failure undergoing hemodialysis.
- Echocardiography combined with continuous Doppler technique effectively detects calcific aortic stenosis.
Implications:
- Early and accurate diagnosis of aortic valve stenosis is vital for managing patients with chronic renal failure.
- Utilizing advanced imaging techniques like echocardiography and Doppler is recommended for improved diagnostic accuracy in this high-risk population.
Abstract:
Chronic renal failure is associated with a high incidence of calcifications of the mitral anulus, which if severe enough may result in mitral stenosis or regurgitation. Aortic valve calcifications, though less frequent, may also occur and cause aortic valve stenosis, as observed in two patients. In hemodialysed patients, identification of valvular aortic stenosis might be difficult on a clinical basis since the systolic ejection murmur might be attributed to aortic sclerosis or a high output state and left ventricular hypertrophy to previous hypertensive disease. Calcific aortic stenosis may easily be detected using echocardiography combined with the continuous Doppler technique.
Related Concept Videos
Mitral Regurgitation I: Introduction
Mitral Stenosis I: Introduction
Mitral Stenosis II: Clinical features and Diagnostic Tests
Mitral Stenosis III: Medical Management
Mitral Stenosis IV: Nursing Management
Hemodialysis II: Procedure and Complications

