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Updated: May 24, 2026
ampliPHOX Colorimetric Detection on a DNA Microarray for Influenza
Published on: June 9, 2011
Precise H1N1 swine influenza detection using stuffer-free multiplex ligation-dependent probe amplification in
Boram Chung1, Gi Won Shin, Hee Sung Hwang
1School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang, Gyeongbuk 790-784, Republic of Korea.
Abstract:
The H1N1 influenza virus has spread worldwide to become pandemic. Here, we developed a new method to discriminate various types of influenza A, including H1N1, using stuffer-free multiplex ligation-dependent probe amplification based on a conformation-sensitive separation method, namely capillary electrophoresis-single-strand conformation polymorphism. Unlike conventional methods, our approach precisely detects five relevant gene markers permitting confirmation of infection.
