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Updated: May 24, 2026

Murine Model for Non-invasive Imaging to Detect and Monitor Ovarian Cancer Recurrence
Published on: November 2, 2014
Ovarian cancer screening
John R van Nagell1, Edward John Pavlik
1Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Kentucky Chandler Medical Center-Markey Cancer Center, Lexington, Kentucky, USA. Jrvann2@email.uky.edu
Abstract:
Annual screening of asymptomatic postmenopausal women using a combination of transvaginal sonography and serum Ca-125 has been evaluated in 4 major clinical trials as a means to facilitate earlier detection of ovarian cancer. In several trials, screening has caused a decrease in stage at detection. These ovarian cancer screening trials are reviewed. The effect of screening on ovarian cancer mortality varies in different trials and is the subject of further investigation.
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