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Computerized tomography in infantile encephalitis.

E B Charney, E J Orecchio, R A Zimmerman

    American Journal of Diseases of Children (1960)
    |August 1, 1979
    PubMed
    Summary
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    Computerized tomographic (CT) scan abnormalities in infants with encephalitis are not limited to herpes simplex virus infections. CT findings can resolve as neurologic deficits improve, aiding diagnosis and prognosis.

    Area of Science:

    • Pediatric Neurology
    • Infectious Diseases
    • Medical Imaging

    Background:

    • Computerized tomographic (CT) findings are established in various pediatric neurologic conditions.
    • Previously, CT scan abnormalities in encephalitis were primarily linked to herpes simplex virus infection.

    Observation:

    • This study describes two infants with encephalitis (one coxsackievirus B2 meningoencephalitis) who exhibited abnormal CT scans during the acute illness phase.
    • Both infants demonstrated resolution of CT abnormalities concurrently with recovery from neurologic and developmental deficits.

    Findings:

    • CT scan abnormalities in infant encephalitis can occur with non-herpes simplex viral infections.
    • The resolution of CT abnormalities correlates with clinical improvement in pediatric encephalitis.

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    Implications:

    • CT imaging may play a role in assessing the diagnosis and prognosis of infants presenting with clinical encephalitis.
    • Expanding the understanding of CT findings in pediatric encephalitis aids clinical management.