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Updated: May 24, 2026

Multiplex Chemical Imaging Based on Broadband Stimulated Raman Scattering Microscopy
Published on: July 25, 2022
Image formation in CARS and SRS: effect of an inhomogeneous nonresonant background medium
K I Popov1, A F Pegoraro, A Stolow
1Department of Physics, University of Ottawa, Ottawa, Ontario, Canada. kpopov@uottawa.ca
Abstract:
We investigate the role of a spatially inhomogenous nonresonant background medium on several Raman-based imaging modalities. In particular, we consider a small resonant bead submerged in a spatially heterogeneous nonresonant χ(3) background. Using detailed 3D electrodynamic simulations, we compare coherent anti-Stokes Raman scattering (CARS), frequency-modulated CARS, amplitude-modulated stimulated Raman scattering (SRS), and frequency-modulated SRS. We find that only FM-SRS is background-free.
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