Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Electrodes: Overview01:17

Electrodes: Overview

Electrochemical measurements are conducted in an electrochemical cell composed of various components that control and measure the current and potential. One fundamental component is electrodes, conductive materials that enable electron transfer reactions at their surfaces.
There are two main types of electrodes in electrochemical cells. The first type, known as the working or indicator electrode, has a potential that is sensitive to the analyte's concentration and reacts to changes in the...
Processes at Electrodes01:30

Processes at Electrodes

The electrode interacts with ions in the electrolyte solution at its interface. The rate of oxidation and reduction depends on the speed at which electrons can transfer through this interface. As ions attach to or leave the electrode surface, the electrode acquires a charge, and an electrical potential forms across the interface, making the process more difficult to reach equilibrium. The charge on the electrode affects the local ion concentrations in the solution, though thermal motion...
Electrochemical Cells01:28

Electrochemical Cells

Electrochemical cells are systems that convert chemical energy into electrical energy or use electrical energy to drive chemical reactions. They consist of two electrodes in contact with an electrolyte, where redox reactions enable electron transfer. Most electrochemical cells include two half-cells connected by an external wire for electron flow and a salt bridge for ion flow. The salt bridge contains an electrolyte solution and maintains charge neutrality by allowing ions—not electrons—to...
Types of Reversible Electrodes01:24

Types of Reversible Electrodes

For electrode reversibility to be maintained, all the reactants and products involved in the half-reaction must be present at the electrode. There are several types of reversible electrodes (half-cells).In metal-metal-ion electrodes, a metal balances electrochemically with a solution of its own ions. Examples are Cu2+|Cu and Zn2+|Zn. Metals that react with the solvent, like group 1 and most group 2 metals, which react with water, and zinc, which reacts with aqueous acidic solutions, cannot be...
Cellular Injury IV: Necrosis01:16

Cellular Injury IV: Necrosis

Necrosis is a form of irreversible cell death caused by severe injury such as ischemia, toxins, or trauma. Unlike programmed cell death, it is an uncontrolled, pathological process that typically provokes inflammation in surrounding tissues.Pathophysiologic ChangesNecrosis begins when cells sustain critical damage, leading to swelling of organelles, particularly mitochondria, and rapid ATP depletion. As energy levels decline, membrane ion pumps fail, leading to calcium influx and eventually,...
Bode Plots Construction01:24

Bode Plots Construction

The Bode plot is an essential tool in control system analysis, mapping the frequency response of a system through a magnitude plot and a phase plot, both against a logarithmic frequency axis. To construct a Bode plot, consider the transfer function H(ω):

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genomic landscape of triple-negative breast cancer in South Asian populations: a systematic review.

BMC cancer·2026
Same author

Genetic and biological determinants of pulmonary embolism: Insights from Mendelian randomization studies.

World journal of experimental medicine·2026
Same author

Use of advanced cardiovascular imaging in rheumatic immune-mediated inflammatory diseases.

Rheumatology (Oxford, England)·2026
Same author

Serum and adipose tissue-derived extracellular vesicles as biomarker reservoirs in oesophageal adenocarcinoma.

Scientific reports·2026
Same author

From Nail Biting to Osteomyelitis: A Pediatric Case of Distal Phalanx Infection Secondary to Onychophagia.

Cureus·2026
Same author

Conditional Reactivation of Lysozyme Nanosystems via Hydrophobic Ion Pairing.

ACS nanoscience Au·2026
Same journal

The Heart of the Metaverse: How Immersive Technologies Are Revolutionizing Cardiac Care.

IEEE pulse·2026
Same journal

Benefits for Early Diagnosis, Treatment, and Research.

IEEE pulse·2026
Same journal

At the Crossroads of Innovation.

IEEE pulse·2026
Same journal

Robotics in the Cath Lab: Precision, Safety, and the Rise of Remote Cardiac Interventions.

IEEE pulse·2026
Same journal

Industry Corner Live With BioBeat CEO Arik Ben Ishay.

IEEE pulse·2026
Same journal

Engineering the Next Generation of Artificial Hearts.

IEEE pulse·2026
See all related articles

Related Experiment Video

Updated: May 24, 2026

A Method for Systematic Electrochemical and Electrophysiological Evaluation of Neural Recording Electrodes
09:27

A Method for Systematic Electrochemical and Electrophysiological Evaluation of Neural Recording Electrodes

Published on: March 3, 2014

Electrode failure: tissue, electrical, and material responses.

Wolfgang Streit1, Qing-Shan Xue, Abhishek Prasad

  • 1Department of Neuroscience, University of Florida, Gainesville, Florida, USA. pschorr@ufl.edu

IEEE Pulse
|February 21, 2012
PubMed
Summary
This summary is machine-generated.

Reliable neural probes are crucial for long-term brain recordings needed for neuroprosthetics. Chronic implantation causes signal degradation, impacting the effectiveness of therapies for neurological disorders.

More Related Videos

Finite Element Modelling of a Cellular Electric Microenvironment
08:23

Finite Element Modelling of a Cellular Electric Microenvironment

Published on: May 18, 2021

Tools for Surface Treatment of Silicon Planar Intracortical Microelectrodes
06:39

Tools for Surface Treatment of Silicon Planar Intracortical Microelectrodes

Published on: June 8, 2022

Related Experiment Videos

Last Updated: May 24, 2026

A Method for Systematic Electrochemical and Electrophysiological Evaluation of Neural Recording Electrodes
09:27

A Method for Systematic Electrochemical and Electrophysiological Evaluation of Neural Recording Electrodes

Published on: March 3, 2014

Finite Element Modelling of a Cellular Electric Microenvironment
08:23

Finite Element Modelling of a Cellular Electric Microenvironment

Published on: May 18, 2021

Tools for Surface Treatment of Silicon Planar Intracortical Microelectrodes
06:39

Tools for Surface Treatment of Silicon Planar Intracortical Microelectrodes

Published on: June 8, 2022

Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Materials Science

Background:

  • Neuroprosthetics offer potential therapies for neurological disorders by interfacing with the central nervous system (CNS).
  • Restoring motor ability requires high-quality, long-term neural signal acquisition.
  • Chronic implantation of neural probes leads to signal and electrode degradation over time.

Purpose of the Study:

  • To investigate the factors contributing to the degradation of neural probe performance after chronic implantation.
  • To understand the time-dependent changes in signal quality, including signal-to-noise ratio, noise floor, peak amplitude, and neuronal yield.
  • To identify the underlying causes of signal degradation related to tissue interfaces.

Main Methods:

  • Review of recent advances in neuroprosthetics development in animal and human studies.
  • Analysis of reported data on the temporal degradation of microelectrode performance post-implantation.
  • Focus on signal characteristics such as signal-to-noise ratio, noise floor, peak amplitude, and neuronal yield.

Main Results:

  • Neuroprosthetics show promise for restoring function by deriving control signals from the CNS.
  • Chronic implantation of microelectrodes results in time-dependent degradation of signal quality.
  • Degradation is linked to issues at the tissue-electrode interface, affecting key signal metrics.

Conclusions:

  • Reliable, long-term neural recording is essential for the success of neuroprosthetic therapies.
  • Understanding and mitigating signal degradation from chronic implantation is critical for patient outcomes.
  • Further research into tissue-electrode interface phenomena is needed to ensure the longevity of neural probes.