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Related Experiment Video

Updated: May 24, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

Awake transapical aortic valve implantation.

Francesco Dimitri Petridis1, Carlo Savini, Andrea Castelli

  • 1Department of Cardiac Surgery, Policlinico S. Orsola-Malpighi, Bologna, Italy. fdpetridis@vodafone.it

Interactive Cardiovascular and Thoracic Surgery
|February 21, 2012
PubMed
Summary

Transapical aortic valve implantation offers a less invasive option for severe aortic stenosis. This case highlights its successful application in an awake patient with severe chronic obstructive pulmonary disease.

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Area of Science:

  • Cardiology
  • Thoracic Surgery
  • Anesthesiology

Background:

  • Severe aortic stenosis poses significant risks for traditional open-heart surgery.
  • Transapical aortic valve implantation (TAVI) is an emerging minimally invasive alternative.
  • Patients with severe chronic obstructive pulmonary disease (COPD) present unique challenges for cardiac procedures.

Observation:

  • A case report detailing an awake transapical aortic valve implantation procedure.
  • The patient had severe aortic stenosis and severe chronic obstructive pulmonary disease.
  • The procedure was performed without general anesthesia.

Findings:

  • Successful implantation of a transapical aortic valve in an awake patient with severe COPD.
  • Demonstrates the feasibility of awake TAVI in high-risk surgical candidates.

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Last Updated: May 24, 2026

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

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Published on: May 21, 2017

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
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Published on: August 8, 2025

  • Highlights effective management of respiratory compromise during the procedure.

    • Implications:

    • Awake TAVI may be a viable option for carefully selected high-risk patients with severe COPD.
    • This approach could expand treatment options for aortic stenosis in complex patient populations.
    • Further research is warranted to assess safety and efficacy across diverse patient groups.