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Updated: May 24, 2026

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging
Published on: December 30, 2016
Pectus carinatum--first ultrastructural findings of a potential metabolic lesion
Christoph Brochhausen1, Felix Karl P Müller, Salmai Turial
1Institute of Pathology, University Medical Centre Mainz, Mainz, Germany. brochhausen@pathologie.klinik.uni-mainz.de
Abstract:
The histological and ultrastructural findings of rib specimens after two re-interventions in the case of recurrence of pectus carinatum (PC) are presented in this report. A 15-year-old boy developed recurrences of mild PC after re-chondroplasties using the Ravitch technique. Histological study of the resected cartilage showed markedly degenerative changes of the sternocostal cartilage. For the first time, intracellular crystalline inclusions in some of the chondrocytes were found. These findings indicate metabolic changes as a possible pathogenetic parameter in PC.
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