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Related Concept Videos

Esophageal Achalasia01:27

Esophageal Achalasia

Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide (VIP)...
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Esophageal Strictures-I: Introduction

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Etiology
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Related Experiment Video

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Primary Sjogren's Syndrome Associated with Lung Adenocarcinoma: Probing the Potential Common Pathogenic Mechanisms and Experimental Verification
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Churg-strauss syndrome.

Subhasish Ghosh1, Maitreyee Bhattacharya, Sandipan Dhar

  • 1Consultant Pulmonologist, AMRI Hospitals, Dhakuria, Kolkata, India .

Indian Journal of Dermatology
|February 21, 2012
PubMed
Summary
This summary is machine-generated.

Churg-Strauss syndrome (CSS), a rare vasculitis, can present with severe skin lesions mimicking Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Syndrome (SJS/TENS). This case highlights CSS as a crucial differential diagnosis in such presentations.

Keywords:
Churg–Strauss syndromegranulomatous necrotizing small vessel vasculitishypereosinophilia and asthmasinusitis

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Area of Science:

  • Rheumatology
  • Dermatology
  • Immunology

Background:

  • Churg-Strauss syndrome (CSS) is a rare small vessel vasculitis.
  • It is characterized by asthma, sinusitis, and hypereosinophilia.
  • Commonly involves pulmonary, skin, GI, and cardiovascular systems.

Purpose of the Study:

  • To report a case of CSS presenting with extensive skin lesions.
  • To highlight CSS as a differential diagnosis for Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Syndrome (SJS/TENS).

Main Methods:

  • Case report of a 27-year-old female patient.
  • Patient presented with painful lower limb swelling, vesicles, ecchymotic patches, and fever post-steroid withdrawal.

Main Results:

  • The patient's presentation mimicked SJS/TENS.
  • This case underscores the diverse cutaneous manifestations of CSS.

Conclusions:

  • CSS should be considered in patients with extensive skin lesions, especially after steroid withdrawal.
  • Early recognition of CSS is vital for appropriate management.