Related Experiment Video
Updated: May 24, 2026
06:31
Transuterine Fetal Tracheal Occlusion Model in Mice
Published on: February 5, 2021
Congenital right hemidiaphragmatic agenesis
Bilal Mirza1, Zahid Bashir, Afzal Sheikh
1Department of Pediatric Surgery, The Children's Hospital and The Institute of Child Health, Lahore, Pakistan.
Lung India : Official Organ of Indian Chest Society
|February 21, 2012
Summary
This case study details the successful surgical repair of congenital diaphragmatic agenesis in an infant. The treatment involved suturing the remaining diaphragm to chest muscles, avoiding prosthetic materials.
Area of Science:
- Pediatric Surgery
- Thoracic Surgery
- Medical Case Reports
Background:
- Congenital diaphragmatic hernia (CDH) is a birth defect where abdominal organs move into the chest.
- Severe cases can involve complete diaphragm agenesis, a rare malformation.
- Infants with CDH often present with respiratory distress.
Purpose of the Study:
- To report a rare case of right hemidiaphragmatic agenesis.
- To describe a successful surgical management technique for this condition.
- To highlight a prosthetic-free approach for diaphragmatic defect repair.
Main Methods:
- A 45-day-old male infant presented with respiratory symptoms.
- Diagnostic imaging revealed a right-sided congenital diaphragmatic hernia.
- Surgical exploration identified agenesis of the right hemidiaphragm.
Main Results:
- A large defect was found, with absence of the diaphragm anteriorly and laterally.
- The posterior rim of the diaphragm was successfully sutured to intercostal muscles and ribs.
- The infant's condition was managed without the need for prosthetic material.
Conclusions:
- Hemidiaphragmatic agenesis is a severe form of congenital diaphragmatic hernia.
- Surgical repair by suturing the diaphragm remnant is a viable treatment option.
- This case demonstrates successful management without prosthetic mesh.
Related Concept Videos
01:25Hiatal Hernia
A hiatal hernia is the abnormal protrusion of the stomach or other abdominal organs through the esophageal hiatus of the diaphragm into the thoracic cavity.Normally, the gastroesophageal junction (GEJ) lies below the diaphragm and is supported by the phrenoesophageal membrane, the diaphragmatic crura, and connective tissues. Weakening of these structures—due to aging, congenital defects like a short esophagus, or increased intra-abdominal pressure from coughing, obesity, pregnancy, or heavy...
01:29Cardiomyopathy III: Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
01:20Mitral Regurgitation I: Introduction
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
01:21Acute Respiratory Failure-II
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
01:22Mitral Stenosis I: Introduction
Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
01:23Rheumatic Heart Disease I: Introduction
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...