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Related Experiment Video

Updated: May 24, 2026

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Published on: December 10, 2016

Empyema caused by Clostridium difficile.

D A Hudson¹, A P Gibb, M J Gill

¹University of Calgary, Calgary, Alberta.

The Canadian Journal of Infectious Diseases = Journal Canadien Des Maladies Infectieuses

|February 21, 2012

Summary

This summary is machine-generated.

Extraintestinal Clostridium difficile infections are uncommon, typically linked to other health issues. This case highlights a rare instance of empyema caused by C. difficile aspiration in a patient with carcinoid syndrome.

Keywords:

Clostridium difficile Empyema Extraintestinal manifestations

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Area of Science:

Infectious Diseases
Gastroenterology
Pulmonology

Background:

Extraintestinal infections caused by Clostridium difficile are infrequently encountered in clinical practice.
Such infections are often correlated with the presence of significant underlying medical conditions.
Clostridium difficile is a bacterium primarily known for causing colitis.

Observation:

A unique case involving a patient diagnosed with carcinoid syndrome and Clostridium difficile colitis was observed.
The patient developed empyema, a condition characterized by the accumulation of pus in the pleural space.
The empyema was attributed to the aspiration of Clostridium difficile.

Findings:

This report details a rare case of empyema stemming from Clostridium difficile.
The patient presented with both carcinoid syndrome and C. difficile colitis, complicating the clinical picture.
The empyema was a direct consequence of aspirating C. difficile into the pleural space.

Implications:

This case expands the understanding of potential extraintestinal manifestations of Clostridium difficile infections.
It underscores the importance of considering C. difficile in the differential diagnosis of empyema, particularly in immunocompromised or critically ill patients.
The association with carcinoid syndrome suggests a potential need for further investigation into specific risk factors or predispositions for such rare complications.