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Updated: Mar 25, 2026

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
Published on: September 27, 2019
DNA sensors with diamond as a promising alternative transducer material
Veronique Vermeeren1, Sylvia Wenmackers, Patrick Wagner
1Biomedical Research Institute, School for Life Sciences, Hasselt University and Transnationale Universiteit Limburg, Agoralaan, Bldg. C, B-3590 Diepenbeek, Belgium;
Abstract:
Bio-electronics is a scientific field coupling the achievements in biology with electronics to obtain higher sensitivity, specificity and speed. Biosensors have played a pivotal role, and many have become established in the clinical and scientific world. They need to be sensitive, specific, fast and cheap. Electrochemical biosensors are most frequently cited in literature, often in the context of DNA sensing and mutation analysis. However, many popular electrochemical transduction materials, such as silicon, are susceptible to hydrolysis, leading to loss of bioreceptor molecules from the surface. Hence, increased attention has been shifted towards diamond, which surpasses silicon on many levels.

