N-[4-(Propyl-sulfamo-yl)phen-yl]acetamide

Area of Science:

• Crystallography
• Organic Chemistry
• Materials Science

Background:

• Understanding the solid-state structure of organic compounds is crucial for predicting their physical and chemical properties.
• Sulfonamide derivatives are important in medicinal chemistry and materials science.
• Detailed structural analysis provides insights into intermolecular forces and crystal packing.

Purpose of the Study:

• To elucidate the crystal structure of the title compound, C(11)H(16)N(2)O(3)S.
• To analyze the molecular geometry, including bond angles and dihedral angles.
• To investigate the intermolecular interactions, such as hydrogen bonding and crystal packing.

Main Methods:

• Single-crystal X-ray diffraction was employed to determine the three-dimensional structure.
• Analysis of crystallographic data included bond length, bond angle, and dihedral angle measurements.
• Intermolecular interactions were identified and characterized using hydrogen bond analysis.

Main Results:

• The sulfur (S) atom exhibits a distorted tetrahedral geometry.
• Significant dihedral angles were observed between the benzene ring and its substituents.
• The crystal structure is characterized by N-H⋯O and C-H⋯O hydrogen bonds, forming C(8) and R(3)(2)(18) motifs.

Conclusions:

• The crystal structure of C(11)H(16)N(2)O(3)S has been successfully determined.
• The study reveals specific geometric parameters and highlights the role of hydrogen bonding in stabilizing the crystal lattice.
• These findings contribute to the understanding of structure-property relationships in organic sulfonamides.