Related Experiment Video
Updated: May 24, 2026

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides (CHIPS)
Published on: June 20, 2014
4-Chloro-2-hy-droxy-N-(4-methyl-phen-yl)benzamide
Abstract:
In the title compound, C(14)H(12)ClNO(2), the dihedral angle between the aromatic rings is 14.87 (11)° and an intra-molecular N-H⋯O hydrogen bond generates an S(6) ring. In the crystal, mol-ecules are linked by O-H⋯O hydrogen bonds, generating C(6) chains propagating along the c-axis direction.
More Related Videos
Related Concept Videos
Hydrolysis of Chlorobenzene to Phenol: Dow Process
NMR Spectroscopy of Benzene Derivatives
Nucleophilic Aromatic Substitution: Elimination–Addition
Reactions at the Benzylic Position: Halogenation
Nomenclature of Aromatic Compounds with Multiple Substituents
For disubstituted benzene derivatives, with two groups attached to the benzene ring, three constitutional isomers are possible. For example, consider dimethyl benzene, often called xylene, where the second methyl group can be substituted at the second, third, or fourth carbon. The relative position of the substituents is represented by prefixes ortho, meta, or...
Electrophilic Aromatic Substitution: Chlorination and Bromination of Benzene

