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Updated: May 24, 2026

Continuous Flow Chemistry: Reaction of Diphenyldiazomethane with p-Nitrobenzoic Acid
Published on: November 15, 2017
Ethyl 2-[(2,4-difluoro-phen-yl)hydrazinyl-idene]-3-oxobutano-ate
Abstract:
The asymmetric unit of the title compound, C(12)H(12)F(2)N(2)O(3), contains two mol-ecules, both of which exist in an E conformation with respect to their C=N bonds [1.321 (6) and 1.310 (6) Å]. The mol-ecular conformations are supported by intra-molecular N-H⋯O hydrogen bonds, which generate S(6) rings. In the crystal, mol-ecules are linked by C-H⋯O and C-H⋯F hydrogen bonds into layers lying parallel to (001). The crystal studied was an inversion twin with a 0.58 (1):0.42 (1) domain ratio.
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