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Related Experiment Video

Updated: May 24, 2026

Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
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Stereotactically guided breast biopsy: a review.

Victoria Ames1, Peter D Britton

  • 1Department of Radiology, Cambridge Breast Unit, Addenbrooke's Hospital, Box 97, Cambridge, UK CB2 2QQ.

Insights Into Imaging
|February 21, 2012
PubMed
Summary

Vacuum-assisted biopsy (VAB) systems offer superior diagnostic accuracy compared to 14-G core biopsy (CB) needles, significantly reducing false-negative rates and the need for further surgical intervention in stereotactic procedures.

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Area of Science:

  • Radiology
  • Pathology
  • Surgical Oncology

Background:

  • Stereotactic biopsy techniques have evolved from analogue mammography add-ons to digital systems.
  • Current methods include 14-G core biopsy (CB) and vacuum-assisted biopsy (VAB) needles.
  • The choice of biopsy device impacts diagnostic accuracy and patient management.

Purpose of the Study:

  • To compare stereotactic equipment and needle types.
  • To evaluate the effect of needle type on pathological results.
  • To assess the impact on subsequent patient management and surgical outcomes.

Main Methods:

  • Review of available stereotactic equipment, including analogue and digital systems.
  • Comparison of 14-G core biopsy (CB) needles and vacuum-assisted biopsy (VAB) systems.

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  • Analysis of false-negative rates and disease underestimation associated with each method.

    • Main Results:

    • Vacuum-assisted biopsy (VAB) systems demonstrate superior performance over 14-G CB.
    • VAB significantly reduces the false-negative rate (0.7% vs. 8% for CB).
    • Underestimation of malignancy is noted for B3 (25%) and B4 (66%) lesions, with higher rates for CB.

    Conclusions:

    • Vacuum-assisted biopsy (VAB) offers improved diagnostic accuracy and reduces the need for repeat surgeries.
    • Meticulous technique and multidisciplinary cooperation are crucial for accurate stereotactic biopsy.
    • Careful patient selection and follow-up are essential, especially for B3 and B4 lesions.