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Published on: June 28, 2024
Pineal cysts in children
Insights
Pineal cysts are common in children and appear similar on MRI regardless of the reason for the scan. These benign findings are a normal variant and do not require further follow-up imaging.
Area of Science:
- Pediatric Radiology
- Neuroimaging
- Cystic Lesions
Background:
- Pineal cysts are frequently identified during pediatric neuroimaging.
- Understanding their prevalence and characteristics is crucial for accurate diagnosis.
Purpose of the Study:
- To determine the prevalence and imaging characteristics of pineal cysts in children undergoing MRI.
- To compare findings between children evaluated for idiopathic short stature (ISS) and central precocious puberty (CPP).
Main Methods:
- Retrospective monocentric study of brain MRI scans in 116 children with ISS and 56 with CPP.
- Analysis of cyst dimensions, wall/septal thickness, signal intensity, and solid components.
- Comparison of prevalence between groups using statistical tests (p < 0.05).
Main Results:
- Comparable prevalence of pineal cysts in ISS (11.2%) and CPP (10.7%) groups.
- Most cysts (74%) had thin septations and showed no changes on follow-up.
- No neurological signs were observed in children with pineal cysts.
Conclusions:
- Benign pineal cysts are a common finding in pediatric populations.
- High-resolution MRI reveals frequent septations, indicative of a normal variant.
- Routine follow-up MRI or contrast administration is generally unnecessary for these findings.
Abstract:
OBJECTIVE: To describe the prevalence and characteristics of pineal cysts found on MRI in children. METHODS: This is a retrospective monocentric study of all brain magnetic resonance imaging (MRI) examinations performed under the same technical conditions for checking the idiopathic nature of short stature (ISS group, n = 116) and for the investigation of central precocious puberty (CPP) over a 3-year period (n = 56). Dimensions, wall and septal thickness, number of locules, signal intensity, and the presence of a solid component were analysed. Ten of 19 cysts were re-evaluated (follow-up interval 4-28 months). The prevalence of the pineal cysts was compared between the two groups using χ2 and Fisher's exact tests, and a significance threshold of p < 0.05. RESULTS: The prevalence of cysts was comparable in the two groups, CPP (10.7%) and ISS (11.2%). Cyst characteristics were similar in the two groups and 74% had thin septations. None of the cysts changed on follow-up. None of the children with pineal cysts exhibited neurological signs. CONCLUSION: Benign pineal cysts are a common finding in young children. High-resolution MRI demonstrates that these cysts are often septated. This pattern is a normal variant and does not require follow-up MR imaging or IV contrast media.
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