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Related Experiment Video

Updated: May 24, 2026

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Published on: February 11, 2022

Eisenmenger syndrome: not always inoperable.

Jing-Bin Huang¹, Jian Liang, Li-Yan Zhou

¹Department of Cardiothoracic Surgery, Affiliated Ruikang Hospital of Guangxi Traditional Chinese Medical College, Nanning, Guangxi Zhuang Autonomous Region, China. b2007117@hotmail.com

Respiratory Care

|February 22, 2012

Summary

Advanced therapies for pulmonary arterial hypertension are making previously inoperable Eisenmenger syndrome patients treatable. A diagnostic-treatment-and-repair strategy now allows safe and effective surgical interventions.

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Last Updated: May 24, 2026

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Published on: February 11, 2022

Area of Science:

Cardiology
Pulmonology
Medical Therapeutics

Background:

Eisenmenger syndrome was historically considered inoperable.
Pulmonary arterial hypertension (PAH) treatments have advanced significantly.
These advancements offer new hope for Eisenmenger syndrome patients.

Purpose of the Study:

To review current knowledge on Eisenmenger syndrome pathophysiology and treatment.
To highlight the impact of new PAH therapies on Eisenmenger syndrome management.
To discuss the feasibility of surgical interventions in the current era.

Main Methods:

Review of recent literature on PAH and Eisenmenger syndrome.
Analysis of the diagnostic-treatment-and-repair strategy.
Evaluation of surgical outcomes with advanced PAH therapies.

Main Results:

Advanced PAH therapies effectively reduce pulmonary vascular resistance and symptoms.
Patients treated with advanced therapies can become candidates for surgery.
A diagnostic-treatment-and-repair strategy enables safe and effective surgical correction.

Conclusions:

Eisenmenger syndrome is now potentially operable with advanced PAH therapies.
Improved diagnosis, preoperative, and surgical management enhance patient outcomes.
Future research may focus on combining vascular remodeling reversal with surgical correction.