Related Experiment Video
Updated: May 24, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Chronic kidney disease, diabetes mellitus and cardiovascular disease: risks and commonalities
Rebecca Suckling1, Hugh Gallagher
1South West Thames Renal and Transplantation Unit, St. Helier Hospital, Carshalton, Surrey, UK.
Insights
Chronic kidney disease (CKD) and diabetes mellitus (DM) are rising globally, increasing cardiovascular disease risk. Early detection and integrated vascular care are crucial for managing these conditions and improving patient outcomes.
Area of Science:
- Nephrology
- Endocrinology
- Cardiology
Background:
- Increasing global prevalence of chronic kidney disease (CKD) and diabetes mellitus (DM).
- CKD and DM are significant risk factors for cardiovascular disease (CVD).
- These conditions represent key components of multimorbidity in aging populations.
Purpose of the Study:
- To highlight the associations between CKD, DM, and CVD.
- To emphasize the importance of shared risk factors.
- To outline strategies for prevention, early detection, and management.
Main Methods:
- Review of shared traditional and nontraditional risk factors.
- Discussion of public health and clinical care targets.
- Emphasis on holistic vascular care approaches.
Main Results:
- CKD and DM significantly elevate CVD risk.
- Shared risk factors necessitate integrated management strategies.
- Effective management requires a combination of prevention, early detection, and treatment.
Conclusions:
- Prevention and early identification of CKD are vital.
- Quantitative proteinuria testing aids risk stratification.
- Optimal management includes renin-angiotensin system antagonists and blood pressure control.
Abstract:
The prevalence of chronic kidney disease (CKD) and diabetes mellitus (DM) is increasing worldwide. CKD and diabetes are important risk factors for cardiovascular disease and all three conditions are key components of the multiple morbidities increasingly evident as population age in the developed world. Shared risk factors, both traditional and nontraditional, contribute to these associations, and are important targets for public health and both primary and secondary care. Prevention and early detection in combination with a holistic approach to vascular care will be key to improving outcomes and reducing costs. Routine reporting of estimated glomerular filtration rate to aid early identification, risk stratification through quantitative proteinuria testing, appropriate use of renin-angiotensin system antagonists and optimal blood pressure control are important strategies to improve the care of people with or at risk of CKD.
Related Concept Videos
Chronic Kidney Disease II: Clinical Manifestations
Chronic Kidney Disease I: Introduction
Diabetic Nephropathy
Chronic Kidney Disease IV: Nursing Management
Chronic Kidney Disease III: Interprofessional Care
Coronary Artery Disease I: Introduction
