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Updated: May 24, 2026

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
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Assertive Community Treatment for alcohol dependence (ACTAD): study protocol for a randomised controlled trial.

Helen Gilburt1, Tom Burns, Alex Copello

  • 1Department of Addictions, Institute of Psychiatry, Kings College London, London, UK.

Trials
|February 22, 2012
PubMed
Summary

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Assertive Community Treatment (ACT) may improve engagement for alcohol-dependent individuals. This study explores ACT

Area of Science:

  • Addiction Medicine
  • Psychiatry
  • Public Health

Background:

  • Alcohol dependence is a major UK health issue with low treatment engagement (6% annually).
  • Conventional treatments struggle to engage patients, particularly those hard to reach.
  • Assertive Community Treatment (ACT), successful in mental health, shows potential for alcohol dependence.

Purpose of the Study:

  • To explore the effectiveness of Assertive Community Treatment (ACT) plus care as usual versus care as usual for alcohol dependence.
  • To assess ACT's impact on hard-to-engage individuals with primary alcohol dependence.
  • To gather data for designing a definitive trial on ACT for alcohol dependence.

Main Methods:

  • Exploratory, single-blind, randomised controlled trial with 90 alcohol-dependent participants.

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  • Intervention group received ACT (intensive outreach, community-based, comprehensive case management) for one year.
  • Primary outcomes: alcohol consumption (drinks per day, abstinence days); secondary outcomes: dependence severity, quality of life, engagement.
  • Main Results:

    • Data collection and analysis are ongoing; results are pending.
    • The study aims to measure changes in alcohol consumption and related outcomes.

    Conclusions:

    • Results will inform the potential benefits of ACT for alcohol dependence.
    • Findings will guide the design of future, larger-scale trials on ACT interventions.