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Updated: May 24, 2026
Mouse Models of Periventricular Leukomalacia
Published on: May 18, 2010
Three-dimensional brain images in preterm children with periventricular leukomalacia
Hsiao-Feng Chou1, Ming-Fan Lin, Chia-Yuan Chen
1Department of Pediatrics, Taipei Medical University-Wan Fang Hospital, Taipei, Taiwan.
Background:
To investigate the use of three-dimensional (3D) brain magnetic resonance imaging (MRI) to evaluate in preterm children with periventricular leukomalacia.
Materials And Methods:
Semiautomated 3D classification of the gray and white tissues was used to reconstruct brain images of patients with confirmed periventricular leukomalacia from 2D MRI.
Results:
We studied 14 preterm patients. The gestational age ranged from 25-37 weeks. The corrected age ranged from 5-49 months. We reconstructed the gray matter, white matter, and ventricles in order to analyze the brain volume.
Conclusion:
Three-dimensional MRI is a good tool that can be used to demonstrate brain lesions in stereo and differentiate the gray matter, white matter, and ventricles. Brain volume can also be accurately evaluated.
