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Related Concept Videos

Increased Body Temperature01:25

Increased Body Temperature

7.5K
A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
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Types of Fever01:25

Types of Fever

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Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
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Methods of reducing fever01:22

Methods of reducing fever

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The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
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Patterns of Fever01:26

Patterns of Fever

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Before understanding the types and patterns of fever, it is essential to know its phases.
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Inflammatory Response I: Vascular and Cellular01:30

Inflammatory Response I: Vascular and Cellular

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The inflammatory response is the body's defense against infection, injury, or irritation from bacteria, trauma, toxins, or heat. Inflammation helps locate and destroy pathogens and remove damaged tissue elements to heal the body. During this initial phase, fluid, blood products, and nutrients migrate to the injured area, resulting in redness, heat, swelling, ache, and loss of function. Moreover, signs of systemic inflammation include fever, increased WBC count, malaise, anorexia, nausea,...
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Homeostatic Imbalances in Body Temperature01:19

Homeostatic Imbalances in Body Temperature

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Hyperthermia occurs when the body's temperature becomes unusually high, often due to heat exposure, intense physical activity, or certain illnesses. This condition can create a dangerous cycle where elevated body temperature increases the metabolic rate, generating more heat and potentially leading to organ failure and brain damage. A severe form of hyperthermia, called heat stroke, can raise body temperature to life-threatening levels. Fever, on the other hand, is a controlled form of...
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Using a Bacterial Pathogen to Probe for Cellular and Organismic-level Host Responses
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Fever: pathogenesis, pathophysiology, and purpose.

H A Bernheim, L H Block, E Atkins

    Annals of Internal Medicine
    |August 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Fever is an adaptive immune response in vertebrates, triggered by microbial stimuli that release endogenous pyrogen. This hormone elevates the brain

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    Area of Science:

    • Immunology
    • Neuroscience
    • Physiology

    Background:

    • Fever is an adaptive immune response in vertebrates.
    • It is triggered by exogenous stimuli activating phagocytes to release endogenous pyrogen.

    Purpose of the Study:

    • To discuss current concepts of endogenous pyrogen production.
    • To explore the role of central transmitters in fever.
    • To examine the function of fever in combating disease.

    Main Methods:

    • The study discusses current concepts and mechanisms.
    • It reviews the role of central transmitters.
    • It analyzes the probable function of fever.

    Main Results:

    • Endogenous pyrogen circulates to the brain's thermoregulatory center, elevating the temperature set-point.
    • Warm-blooded animals increase heat production or reduce heat loss to generate fever.
    • Cold-blooded animals use behavioral mechanisms to regulate body temperature.

    Conclusions:

    • Fever is a complex physiological response involving the immune and nervous systems.
    • Understanding fever mechanisms is crucial for comprehending disease combating strategies.
    • Further research into endogenous pyrogen and central transmitters is warranted.