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Updated: May 24, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
The cutaneous manifestations of metastatic malignant melanoma
Kurtis B Reed1, Robert H Cook-Norris, Jerry D Brewer
1Department of Dermatology, Mayo Clinic, Rochester, MN 55905, USA.
Abstract:
Cutaneous metastases are common sequelae of primary malignant melanoma. Because patients with melanoma are examined frequently after diagnosis, it is important that dermatologists are aware of the range of findings that may represent metastatic disease. Many case reports and a few retrospective series have been published detailing the wide variety of clinical presentations of cutaneous metastatic melanoma. This article reviews the various manifestations of metastatic melanoma of the skin and oral mucous membranes and summarizes treatment options for metastatic disease.
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