Related Experiment Video

Updated: May 24, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Risk factors for pediatric intensive care admission in children with acute asthma

Gerbrich E van den Bosch1, Peter J F M Merkus, Corinne M P Buysse

  • 1Department of Pediatric Intensive Care, Erasmus Medical Center-Sophia, Rotterdam, The Netherlands. g.vandenbosch@erasmusmc.nl

Respiratory Care
|February 22, 2012
PubMed

Insights

Identifying risk factors for pediatric intensive care unit (PICU) admission in children with severe acute asthma is crucial. Key factors include smoking, allergies, prior asthma hospitalizations, and non-sanitized home environments.

Area of Science:

  • Pediatric Pulmonology
  • Critical Care Medicine
  • Environmental Health

Background:

  • Severe acute asthma in children leads to significant illness and often necessitates pediatric intensive care unit (PICU) admission.
  • Understanding risk factors for PICU admission is vital for proactive management.

Purpose of the Study:

  • To identify and analyze risk factors associated with PICU admission for severe acute asthma in children.

Main Methods:

  • Retrospective, multicenter case-control study design.
  • Matched cases (PICU admission for asthma) and controls (no PICU admission for asthma) based on sex, age, hospital, and time since asthma diagnosis.
  • Analysis of fourteen potential risk factors using univariate and multivariate logistic regression.

Main Results:

  • Sixty-six cases were matched with 164 controls.
  • Multivariate analysis identified four significant risk factors for PICU admission: active or passive smoking, allergies, previous asthma hospitalization, and a non-sanitized home environment.

Conclusions:

  • Awareness of identified risk factors is essential for healthcare providers and parents.
  • Interventions targeting these risk factors may help reduce PICU admissions for severe acute asthma in children.
Abstract

More Related Videos

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device09:36

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device

Published on: September 24, 2020

Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include: