Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Escape Velocity01:26

Escape Velocity

The escape velocity of an object is defined as the minimum initial velocity that it requires to escape the surface of another object to which it is gravitationally bound and never to return. For example, what would be the minimum velocity at which a satellite should be launched from the Earth's surface such that it just escapes the Earth's gravitational field?
To calculate the escape velocity, it is assumed that no energy is lost to any frictional forces. In practice, a satellite launched from...
Computed Tomography01:10

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Prismatic Beams: Problem Solving01:15

Prismatic Beams: Problem Solving

In the design of a supported timber beam subjected to a distributed load, both the beam's physical dimensions and the timber's characteristics, such as its grade and species, are critical. These factors determine the allowable stress values, which are crucial for calculating the necessary beam depth to ensure structural integrity and safety.
The design begins with analyzing the beam as a free body to identify moments and force balances, thereby determining support reactions. Next, the designer...
Leaky Scanning02:28

Leaky Scanning

During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R stands for...
Masonry01:28

Masonry

Masonry, known for its strength, durability, and aesthetic versatility, encompasses construction with solid stone or man-made units like bricks, clay tiles, terra cotta, and concrete blocks, combined to form structures like walls, floors, and arches. These units are placed in a systematic fashion, known as coursing, and are bound together using mortar—a mixture typically made of water, cement, and sand.
The process of building with masonry is hands-on and can be executed with basic tools. A...
Morphogenesis02:19

Morphogenesis

Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cluster Analysis of Migraine-Associated Symptoms (CAMS) across the lifespan: a cross-sectional study.

BMC neurology·2026
Same author

Evaluating chest-worn light logger adherence: development and application of a wear/non-wear model.

Scientific reports·2026
Same author

Headache-associated photophobia is more prevalent during winter: A cross-sectional study from a pediatric headache registry.

Headache·2026
Same author

Amplifying and ameliorating light avoidance in mice with photoreceptor targeting and calcitonin gene-related peptide sensitization.

Headache·2025
Same author

Daily light exposure habits of youth with migraine: a prospective exploratory study.

Npj biological timing and sleep·2025
Same author

Identifying chest-worn light logger adherence: a validation study.

medRxiv : the preprint server for health sciences·2025

Related Experiment Video

Updated: May 24, 2026

Voxel Printing Anatomy: Design and Fabrication of Realistic, Presurgical Planning Models through Bitmap Printing
11:36

Voxel Printing Anatomy: Design and Fabrication of Realistic, Presurgical Planning Models through Bitmap Printing

Published on: February 9, 2022

FIASCO, VoxBo, and MEDx: behind the code.

Geoffrey K Aguirre1

  • 1University of Pennsylvania, PA, USA. aguirreg@mail.med.upenn.edu

Neuroimage
|February 22, 2012
PubMed
Summary

The early development of Blood-Oxygen-Level-Dependent functional Magnetic Resonance Imaging (BOLD fMRI) software was influenced by the internet and open-source movements. This history highlights the evolution and survival of key neuroimaging tools like FIASCO and VoxBo.

Area of Science:

  • Neuroimaging
  • Open-source software development
  • Functional Magnetic Resonance Imaging (fMRI)

Background:

  • The advent of Blood-Oxygen-Level-Dependent functional Magnetic Resonance Imaging (BOLD fMRI) coincided with significant technological advancements.
  • The rise of the internet and the open-source software movement fostered innovation in scientific computing.
  • Numerous neuroimaging software projects emerged during this period, driven by the collaborative and accessible nature of open-source development.

Observation:

  • The survival rate of early open-source neuroimaging projects varied significantly.
  • Two notable projects, FIASCO and VoxBo, emerged during this formative era.
  • Connections were observed between commercial software (MedX at NIH) and unrelated fields like satellite reconnaissance.

Findings:

More Related Videos

Pioneering Patient-Specific Approaches for Precision Surgery Using Imaging and Virtual Reality
06:18

Pioneering Patient-Specific Approaches for Precision Surgery Using Imaging and Virtual Reality

Published on: April 5, 2024

Related Experiment Videos

Last Updated: May 24, 2026

Voxel Printing Anatomy: Design and Fabrication of Realistic, Presurgical Planning Models through Bitmap Printing
11:36

Voxel Printing Anatomy: Design and Fabrication of Realistic, Presurgical Planning Models through Bitmap Printing

Published on: February 9, 2022

Pioneering Patient-Specific Approaches for Precision Surgery Using Imaging and Virtual Reality
06:18

Pioneering Patient-Specific Approaches for Precision Surgery Using Imaging and Virtual Reality

Published on: April 5, 2024

  • The open-source environment facilitated the creation and distribution of novel neuroimaging tools.
  • FIASCO and VoxBo represent successful examples of early BOLD fMRI software development.
  • The narrative reveals unexpected interconnections between medical imaging software and other technological domains.

Implications:

  • Understanding the history of neuroimaging software development provides context for current tools.
  • The success of open-source projects underscores their importance in scientific advancement.
  • Exploring the links between different software domains can inspire cross-disciplinary innovation.