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Updated: May 24, 2026

Breeding by Design for Functional Rice with Genome Editing Technologies
Published on: January 3, 2025
An integrated approach to crop genetic improvement
Martin A J Parry1, Malcolm J Hawkesford
1Rothamsted Research, Plant Science Department, Harpenden, Hertfordshire AL5 2JQ, UK. martin.parry@rothamsted.ac.uk
Global food security is threatened by increasing demand and climate change impacts on crop yields. Novel breeding strategies, including high-throughput phenotyping, are crucial for enhancing crop production and resource use efficiency to meet future needs.
Area of Science:
- Agricultural Science
- Plant Breeding
- Genetics
Background:
- Global food security is challenged by a fragile balance between crop supply and demand.
- Rising populations, increased wealth, and non-food uses escalate agricultural demands.
- Climate change, urbanization, and land degradation limit crop production increases.
Purpose of the Study:
- To address the urgent need to increase food production by at least 70% by 2050.
- To develop novel, integrated approaches for enhancing crop production per unit area.
- To improve the resource use efficiency of crops through advanced breeding techniques.
Main Methods:
- Utilizing high-throughput phenotyping to analyze complex multigenic traits.
- Employing molecular plant breeding to identify genes and quantitative trait loci (QTLs).
- Adopting a multidisciplinary approach to understand genotype-phenotype-environment interactions.
Main Results:
- Identified complex multigenic traits (yield potential, stability, nutrient/water use) as targets for improvement.
- Demonstrated the potential of molecular breeding to enhance crop traits once underlying genes are identified.
- Highlighted the necessity of considering trait interactions, which is challenging for traditional methods.
Conclusions:
- Molecular plant breeding offers substantial potential for improving crop yields and resource use efficiency.
- A multidisciplinary approach is essential for understanding crop improvement processes and identifying candidate genes.
- Incorporating identified traits into new cultivars via conventional or biotechnological tools is key to future crop development.
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