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Syntheses of (-)-pelletierine and (-)-homopipecolic acid
Wen-Hua Chiou1, Guei-Tang Chen, Chien-Lun Kao
1Department of Chemistry, National Chung Hsing University, Taichung, Taiwan 402, R.O.C. wchiou@dragon.nchu.edu.tw
Organic & Biomolecular Chemistry
|February 22, 2012
Abstract:
Enantiomeric syntheses of (-)-homopipecolic acid and (-)-pelletierine have been achieved by chiral resolution of tropanol followed by Baeyer-Villiger oxidation. The methodology provides a practical route for the synthesis of optically pure piperidines.
