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Related Concept Videos

Hormonal Regulation01:33

Hormonal Regulation

The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
Hormonal Regulation01:40

Hormonal Regulation

Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
Diabetic Ketoacidosis ll: Pathophysiology01:22

Diabetic Ketoacidosis ll: Pathophysiology

Diabetic ketoacidosis (DKA) is a metabolic emergency characterized by hyperglycemia, ketonemia, and metabolic acidosis. It results from severe insulin deficiency and an excess of counterregulatory hormones, leading to uncontrolled lipolysis, ketogenesis, and widespread electrolyte and fluid disturbances.Pathophysiology The central event in DKA is a profound loss of insulin action. Without insulin, glucose uptake in insulin-dependent tissues is impaired, while hepatic glucose production...
The Endocrine System01:29

The Endocrine System

The endocrine system is an extensive network of glands – organs or tissues in the body that create chemicals that control many bodily functions, that secrete hormones, which are chemical messengers that play essential roles in regulating various bodily functions. These hormones are secreted into the bloodstream and travel throughout the body. They require specific receptors to convey signals to cells possessing these corresponding receptors. This complex signaling mechanism ensures that every...
Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
Adrenal Gland Disorders01:27

Adrenal Gland Disorders

Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...

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Updated: May 24, 2026

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas
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[Endocrine emergencies during pregnancy].

B Harbeck1, M Schütt, F Sayk

  • 1Medizinische Klinik I, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland. birgit.harbeck@uk-sh.de

Medizinische Klinik, Intensivmedizin Und Notfallmedizin
|February 22, 2012
PubMed
Summary
This summary is machine-generated.

Endocrine emergencies in pregnancy pose serious risks to mothers and fetuses. This review covers diagnosis and management of conditions like Grave

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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

Area of Science:

  • Endocrinology
  • Obstetrics
  • Maternal-Fetal Medicine

Context:

  • Pregnancy involves significant physiological changes that can exacerbate pre-existing endocrine disorders or trigger new ones.
  • Endocrine emergencies during pregnancy present unique diagnostic and management challenges due to altered clinical signs and laboratory values.
  • Conditions such as Grave's disease, type 1 diabetes, and adrenal insufficiency require careful monitoring and intervention.

Purpose:

  • To review the recognition and management of endocrine emergencies complicating pregnancy.
  • To highlight the challenges in diagnosing and treating these conditions due to pregnancy-specific modifications.
  • To discuss the limited therapeutic options and stricter goals in pregnant patients.

Summary:

  • Endocrine emergencies during pregnancy, including Grave's disease, type 1 diabetes, and adrenal insufficiency, can be life-threatening.
  • Diagnosis is complicated by pregnancy-induced symptom modification and altered laboratory reference ranges.
  • Management requires careful consideration of limited pharmacological options and stricter therapeutic targets for maternal and fetal well-being.

Impact:

  • Provides critical information for clinicians managing pregnant patients with endocrine emergencies.
  • Aims to improve maternal and fetal outcomes by emphasizing early diagnosis and appropriate management strategies.
  • Contributes to the understanding of pregnancy-specific endocrinopathies and their acute complications.