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Exercise stress echocardiography after childhood Ross surgery: functional outcome in 26 patients from a single
Linda B Pauliks1, J Brian Clark, Ashley Rogerson
1Department of Pediatric Cardiology, Penn State Hershey Children's Hospital, Hershey, PA 17033, USA. lpauliks@hmc.psu.edu
Insights
Pediatric Ross surgery for aortic valve disease shows good functional results in children. Most young patients achieved normal exercise capacity, even with some right-ventricular outflow tract obstruction.
Area of Science:
- Cardiology
- Pediatric Cardiac Surgery
- Echocardiography
Background:
- Adult studies indicate superior functional outcomes with pulmonary autografts in aortic valve replacement.
- Limited data exists on functional results of the Ross procedure in pediatric patients.
Purpose of the Study:
- To evaluate functional results using exercise stress echocardiography in children after the Ross procedure.
- To assess the impact of right-ventricular outflow tract (RVOT) obstruction on exercise capacity in pediatric patients.
Main Methods:
- Retrospective cohort study of 26 pediatric patients (<17 years) who underwent the Ross procedure.
- Analysis of Bruce protocol stress echocardiograms performed post-surgery.
- Assessment of exercise time and RVOT gradients at rest and during exercise.
Main Results:
- 87% of patients demonstrated normal exercise times (mean 12.8 min).
- RVOT gradients increased significantly post-exercise (38 mmHg to 82 mmHg).
- Mild to moderate RVOT obstruction did not significantly affect exercise capacity.
Conclusions:
- Exercise stress echocardiography is valuable for assessing pediatric patients post-Ross surgery.
- The Ross procedure in children generally yields good exercise capacity.
- RVOT obstruction severity did not correlate with reduced exercise performance in this cohort.
Abstract:
Adult studies suggest a better functional outcome after aortic valve replacement with a pulmonary autograft compared with mechanical or homograft valves. Little is known about functional results after Ross surgery in growing children. This study reports formal exercise stress echocardiographic data from 26 pediatric Ross patients. A retrospective cohort study analyzed stress echocardiographic data of patients who underwent Ross surgery as a child (<17 years old). All patients were operated by a single surgeon and underwent a Bruce protocol stress echocardiogram on the treadmill. Twenty-six patients (4 girls) were 9.3 ± 5.0 years at surgery and 14.9 ± 3.5 years (range 6.6-19.7 years) at follow-up. Mean follow-up was 5.4 ± 3.7 years (median 4.2). All were asymptomatic. The exercise time was normal in 87% of cases at 12.8 ± 2.5 min. On stress echocardiography, the mean right-ventricular outflow tract (RVOT) gradient increased from 38 ± 22 mmHg at rest to 82 ± 33 mmHg after exercise, but this did not correlate with exercise times. Stress echocardiography is useful in evaluating patients after childhood Ross surgery for aortic valve disease. In this pediatric cohort, most patients achieved normal exercise capacity. The presence of mild or moderate RVOT obstruction had no significant impact on exercise capacity.
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