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Related Experiment Video

Updated: May 24, 2026

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
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Necrotizing enterocolitis in multiple gestations: comparison with singletons.

N Zampieri1, C Zamboni, F S Camoglio

  • 1Department of Anesthetic and Surgical Sciences, Pediatric Surgical Unit, University of Verona, Verona, Italy. dr.zampieri@libero.it

Minerva Pediatrica
|February 22, 2012
PubMed
Summary
This summary is machine-generated.

Necrotising enterocolitis (NEC) is more common in multiple pregnancies, especially with severe prematurity. Gestational age under 28 weeks and low Apgar scores are key risk factors for NEC in all newborns.

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Area of Science:

  • Neonatalogy
  • Perinatology
  • Pediatric Surgery

Background:

  • Necrotising enterocolitis (NEC) is a serious gastrointestinal condition affecting newborns.
  • Multiple pregnancies present unique challenges in neonatal care.

Purpose of the Study:

  • To determine the incidence of NEC in multiple versus single pregnancies.
  • To identify risk and morbidity factors associated with NEC in these groups.

Main Methods:

  • Retrospective analysis of neonatal patient records from January 2002 to January 2009.
  • Comparison of NEC incidence and risk factors between multiple and single pregnancies.
  • Inclusion criteria were applied to analyze relevant clinical data.

Main Results:

  • NEC incidence was 18% in multiple pregnancies vs. 4% in single pregnancies (P<0.05).
  • Delayed meconium discharge (5 vs. 2 days) and intestinal washing from day 2 were associated with NEC.
  • Lower gestational age and low Apgar scores were linked to increased mortality.

Conclusions:

  • Higher NEC incidence in multiple births is linked to gestational age and prematurity.
  • Gestational age <28 weeks and low Apgar scores are significant risk factors for NEC in both groups.
  • Early intervention with intestinal washing may prevent NEC development.